K08.2
Conditions
Interventions
Group 1: Patients who have received soft tissue augmentation (with NovoMatrix) upon implantation due to a medical indication.
Group 2: Patients who, due to a medical indication, did not receive any so
Sponsors
Universitätsklinik für Zahn, Mund- und Kieferheilkunde Klinik für Mund-, Kiefer- und Gesichtschirurgie
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) Patients who receive an implant treatment due to a medical indication with soft tissue augmentation (with NovoMatrix) or without soft tissue augmentation at the same time as implantation. 2) People over the age of 18 in the sense of the age of majority, as well as full legal capacity (§§ 2 BGB). 3) Non-smokers and moderate smokers = 20 cigarettes / day 4) Good oral hygiene and plaque control of the patient (full mouth plaque score = 25%) 5) The patient that was informed about the follow-up examinations and agrees to participate in them.
Exclusion criteria
Exclusion criteria: 1) Dependent persons or persons in custody 2) General diseases that contradict dental implant therapy (e.g. diabetes mellitus not ceased) 3) Previous history of non-compliance and / or unreliability) 4) Diseases of the mucous membrane (e.g. erosive lichen planus) 5) Untreated endodontic or periodontal lesions with probing of the PD of = 4mm directly adjacent to the planned implant position 6) Patients with inadequate oral hygiene (full mouth plaque score> 25%) or gingivitis 6) Heavy nicotine abuse (> 20 cigarettes / day) or consumption of chewing tobacco 7) Pregnant or breastfeeding women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Immunohistological reaction in the tissue preparation: distribution pattern of the Macrophages or foreign body giant cells, T cells, neutrophils, monocytes and fibroblasts. | — |
Secondary
| Measure | Time frame |
|---|---|
| Distribution pattern of the porcine Gala1-3Gal epitopes contained in the sample material. | — |
Countries
Germany
Contacts
Public ContactTobias Fretwurst
Universitätsklinik für Zahn, Mund- und Kieferheilkunde Klinik für Mund-, Kiefer- und Gesichtschirurgie
Outcome results
None listed