K02.9
Conditions
Interventions
Group 1: Test group:
750 ml fruit juice drink daily with a polyphenol content of 1.5 g/L
Group 2: Control group: 750ml fruit juice drink daily without additives
Sponsors
Universitätsklinikum Schleswig-Holstein Campus Kiel
Eligibility
Sex/Gender
Male
Age
21 Years to 55 Years
Inclusion criteria
Inclusion criteria: Visible soft and hard plaque
Exclusion criteria
Exclusion criteria: 29.5 kg/m², metabolic or endocrine diseases, malabsorption syndrome, allergies, smoking, alcohol and drug abuse, use of supplements (food additives), antidepressants, antibiotics, fructose intolerance, the presence of a defibrillator or pacemaker, a nickel allergy, known allergies to the study materials used, an MRI examination scheduled during the study period, reflux disease, bulimia, diseases (such as HIV, hepatitis or diabetes) and epilepsy Erosions or carious defects on the teeth requiring treatment, professional dental cleaning less than 4 weeks ago, a periodontal screening index (PSI) >2, no stable occlusion, orthodontic treatment carried out at the time of the study, wearing an occlusal splint ('grinding splint') and no sufficient number of teeth, i.e. no terminal molar in the fourth or third quadrant and more than 2 missing teeth per quadrant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Observation of caries development on the bovine enamel samples after 14 days with the aid of microscopic and scanning electromicroscope evaluation. Depth determination of (de)mineralization analogous to caries development | — |
Secondary
| Measure | Time frame |
|---|---|
| pH measurement, metabolome, microbiome, Blood glucose value | — |
Countries
Germany
Contacts
Public ContactChristof E Dörfer
Klinik für Zahnerhaltungskunde und Parodontologie im UKSH, Campus Kiel
Outcome results
None listed