Corona -Virus-Diesease-2019
Conditions
Interventions
Group 1: Patients testing positive for SARS-CoV-2 will have blood samples collected at specific intervals (acute, day 2, 5, 10, and 30) and analyzed and interpreted for hemorheology, erythrocyte struc
Sponsors
Universitätsklinikum Ulm, Zentrum für Innere Medizin, Sektion Sport- und Rehabilitationsmedizin
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: proven positive Covid 19 infection
Exclusion criteria
Exclusion criteria: 1. refusal of blood collection during standard clinical examinations. 2. acute comorbidities that could affect study variables or pose a safety risk to the participant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The study will prospectively investigate pathomechanisms of SARS-CoV-2 in acutely ill patients and on day 2, 5, 10 and 30. 1. erythrocytes: the deformability of critically ill patients with COVID-19 is significantly reduced compared to the normal population. 2 Inflammation: Inflammatory parameters such as interleukins. 3. non-inflammatory laboratory parameters are suitable to identify severely ill patients with COVID-19. The combination of acute and long-term inflammatory and haemorheological data will provide clues to possible impairments in acute and long-term COVID-19 symptoms. | — |
Secondary
| Measure | Time frame |
|---|---|
| - detection of microparticles in blood plasma after obtaining platelet-free plasma (PFP) after ultradensity centrifugation - morphological changes of RBC via electron microscopy - general blood count changes | — |
Countries
Germany
Contacts
Public ContactJürgen M. Steinacker
Sektion Sport- und Rehabilitationsmedizin
Outcome results
None listed