experimental gingivitis model in healthy patients
Conditions
Interventions
Group 1: experimental gingivitis for 7 days (no tooth brushing in the upper jaw from 24-27),followed by 2 weeks of routine tooth brushing, participants eat their normal diet during the study period, m
Sponsors
Abteilung für Parodontologie, Oralmedizin und Oralchirurgie, CharitéCentrum für Zahn-, Mund- und KieferheilkundeCharité – Universitätsmedizin Berlin
Eligibility
Sex/Gender
All
Age
18 Years to 69 Years
Inclusion criteria
Inclusion criteria: - for the Bahai-group: member of the bahai congregation, planning to fast - age 18-69 years -periodontal healthy - number of teeth: > =24 - no dental treatment required
Exclusion criteria
Exclusion criteria: -for the Bahai group: no complete fasting is intended - pregnancy, lactation, severe systemic diseases, eating disorders or other type of practiced diet-restriction, psychatric diseases - participation in another study - antibiotic treatment 5cigarettes/day -no complete fasting or not following oral hygiene study protocol - probing depth > 3mm, gingival bleeding index > 15%
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| bleeding on probing measured with a pressure sensitive periodontal probe at baseline, after 7, 14 and 19 days | — |
Secondary
| Measure | Time frame |
|---|---|
| sulcus fluid flow rate (periotron device) pH level saliva plaque levels blood parameters (glucose, CRP, IL-6, HDL, LDL, TRG) BMI weight BIA waist at baseline, after 7 says of fasting, 14 and 19 days 4 weeks of glucose monitoring (CGM) with a sensor 1 week before and during fasting validated questionnaires: FEE (Wolfradt, 2013) and Mystizismus (Demmrich et al 2020) 15 intems about diet (Mähler et al 2021) WHO-5 (qualité of life) HADS (Anxiety and Depression) CSS (Stress) OHIP-21 (oral health impact profile) | — |
Countries
Germany
Contacts
Public ContactChristina Laetitia Pappe
Abteilung für Parodontologie, Oralmedizin und Oralchirurgie,CharitéCentrum für Zahn-, Mund- und KieferheilkundeCharité – Universitätsmedizin Berlin
Outcome results
None listed