K05.3
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: age 18-75 years western-diet (daily consumption of sugar) planned periodontal therapy diagnosis: generalized periodontitis, grade A-B, stage I-III, BOP >30%, last subgingival debridement >2 years ago, smoking < 5 cigarettes/day, BMI 18-30, mild systemic disease without known effects on periodontal inflammation
Exclusion criteria
Exclusion criteria: periodontitis stage IV, grade C, diabetes (treated with medication), treatment with anticoagulant, antibiotics in last 3 months, cortisol, pregnancy, lactation, severe systemic diseases, eating disorder, severe psychological disorders, participating in another study, orthodontic treatment/appliance, xerostomia, smoking >5 cigarettes/day, ongoing dental treatment other than periodontal intervention)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bleeding on Probing at baseline, after 4 and 8 weeks of periodontal treatment, with a pressure-sensitive periodontal probe | — |
Secondary
| Measure | Time frame |
|---|---|
| PISA (periodontal inflamed surface area) Periodontal pocket debt plaque index gingival bleeding index bmi waist circumference weight BIA FFQ OHIP-21 HbA1c at baseline, 4 and 8 weeks after treatment continuous Glucose monitoring (2 weeks before and 2 weeks after treatment); microbiological and salivary samples; diatary diary | — |
Countries
Germany
Contacts
Abteilung für Parodontologie, Oralmedizin und Oralchirurgie,CharitéCentrum für Zahn-, Mund- und KieferheilkundeCharité – Universitätsmedizin Berlin