Adolescents
Conditions
Interventions
Group 1: Study phase 1: Screening study on energy drink consumption and other lifestyle factors (approximately n=5000).
Study phase 2: Study of cardiovascular changes in adolescents with chronic high
Sponsors
Bundesinstitut für Risikobewertung
Eligibility
Sex/Gender
All
Age
15 Years to 18 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria study phase 1: - Pupils aged 15 to 18 from Berlin grammar schools, integrated secondary schools, upper secondary schools and vocational schools in grades 9 - 12 or in years 1 - 3 of vocational training. - Pupils can only participate in the online survey after submitting a signed declaration of consent. Inclusion criteria study phase 2: - Pupils from study phase 1 - Signed consent form for the cardiological examination from the pupils and, if applicable, from the parents or legal guardians in the case of underage students (15 - 17 years). - Students must have health insurance and consent to report clinically relevant findings. - Only adolescents who have a chronically high consumption of EDs (EDs on at least 4 days per week with a daily intake of > 3 mg caffeine per kg body weight) will be included in the high-consumption group. - The control group will include only adolescents who consume a maximum of one glass or cup (250 ml) of a caffeinated beverage once a week but do not consume EDs.
Exclusion criteria
Exclusion criteria: Exclusion criteria study phase 1: - Age under 15 years - Age over 18 years - Informed consent was not signed Exclusion Criteria Study Phase 2: - Age under 15 years - Age over 18 years - Informed consent was not signed by pupil or parent/guardian - No existing health insurance - Acute infection including acute covid19 infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Left ventricular ejection fraction, left ventricular mass index (LVMI), mitral annular plane systolic excursion (MAPSE), tricuspid annular plane systolic excursion (TAPSE), global longitudinal strain (GLS), and mitral E/e' average septal and lateral ratio | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure, electrocardiogram (ECG) lead, lifestyle factors such as leisure time activities and health behaviors (especially dietary habits, intake of supplements, smoking, and alcohol consumption) | — |
Countries
Germany
Contacts
Public ContactJuliane Menzel
Bundesinstitut für Risikobewertung
Outcome results
None listed