pain
Conditions
Interventions
Group 1: Placebogroup - Participants receive a nasal spray, with the instruction, that with 50% chance will contain Fentanyl, a powerful analgesic
Group 2: Controlgroup - Participants receive a nasal
Sponsors
Institut für Systemische Neurowissenschaften, Universitätsklinikum Hamburg-Eppendorf
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Healthy participants of full age, able to provide informed consent and capable to reliably rate pain 2. Body mass index: 18 - 30
Exclusion criteria
Exclusion criteria: 1. acute of chronic somatic or psychiatric illness 2. MR-specific exclusion criteria 3. Participating in drug studies 4. regular drug use 5. intake of painkillers within 24 hours of study procedures 6. Use of illegal substances 7. pregnancy of breast feeding 8. acute skin disease or lesion on stimulation sites 9. acute nose disease or lesion 10. analgesic medication or capsaicin allergies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The aim of the study is to investigate whether active placebos (placebo with side effects) lead to larger placebo effects than passive placebos (placebo without side effects) | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary Aim is to investigate the neual underpinnings of active placebo effects | — |
Countries
Germany
Contacts
Public ContactLieven Schenk
Institut für Systemische Neurowissenschaften, Universitätsklinikum Hamburg-Eppendorf
Outcome results
None listed