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The effect of alcohol on perceived trustworthiness: moderation and oxytocin-induced mediation

The effect of alcohol on perceived trustworthiness: moderation and oxytocin-induced mediation - AlOxTrust

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00026599
Enrollment
78
Registered
2021-12-21
Start date
2022-02-04
Completion date
Unknown
Last updated
2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Trustworthiness of presented faces in relation to alcohol consumption

Interventions

Group 1: The subjects consume alcohol in the presence of the experimenter. Perceived trustworthiness is assessed twice (before and after consumption). Group 2: The subjects consume an non-alcohol beve

Sponsors

Zentralinstitut für Seelische Gesundheit Mannheim (ZI)
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Male gender; "social drinker" (regular consumption of alcohol with breath alcohol levels of at least 1.5 per mille, preferably in social contexts); = 18 years of age; Last meal eaten 3 hours before the start of the survey; Last cigarette smoked 3 hours before start of survey; On the day of the survey, the subject refrains from sexual activity; On the day of the survey, the subject refrains from increased physical activity; On the day of the survey, the subject does not consume more than 0.5 liters of fluid; On the day of the survey, the subject does not expose him/herself to excessive stress

Exclusion criteria

Exclusion criteria: Current and/or previous presence of a diagnosed psychotic or depressive mental illness; Current and/or previous presence of a diagnosed alcohol-related addictive disorder (assessment using the AUDIT; Rumpf, H.J., Meyer, C., Hapke, U., John, U., 2003. German version of the Alcohol Use Disorders Identification Test (AUDIT-G-L). In: Glöckner-Rist, A., Rist, F., Küfner, H. (Eds.), Electronic Handbook on Survey Instruments in the Field of Addiction (EHES). Version 3.00. Center for Surveys, Methods and Analyses, Mannheim); Current psychotherapeutic treatment of a mental illness; Current use of medications that may interact with alcohol (e.g., antidepressants, sedatives); Current presence of a serious physical disease: oncological therapy during the past 10 years, metabolic disease (Addison's disease, Cushing's disease, hypogonadism, testosterone treatment), neurological disease (multiple sclerosis, M. Parkinson's disease, amyotrophic lateral sclerosis, stroke during the past 5 years, traumatic brain disease with persistent neurological deficit), acute cardiovascular disease (first manifestation during the past 4 weeks), myocardial infarction, decompensated heart failure, renal failure, infectious disease currently under treatment, rheumatologic disease; Use of illicit drugs in more than 15 instances over a lifetime (cannabis excluded); Use of illicit drugs in the last 7 days (cocaine, opioids, amphetamines; cannabis excluded); Known intolerance to substances containing alcohol (alcohol sensitivity or alcohol intolerance); use of steroid hormone preparations (incl. anabolic steroids) within the last 12 months.

Design outcomes

Primary

MeasureTime frame
Subjects' perceived trustworthiness regarding presented faces, measured via behavioral test.

Secondary

MeasureTime frame
Oxytocin concentration in the salvia.

Countries

Germany

Contacts

Public ContactLeonard Wenger

Zentralinstitut für Seelische Gesundheit (ZI)

Leonard.Wenger@zi-mannheim.de015206571154

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026