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Clinical, prospective, randomised and controlled multicentric split-mouth study to evaluate the healing of an extraction socket with and without autologous, xenogenic or alloplastic bone substitute material

Clinical, prospective, randomised and controlled multicentric split-mouth study to evaluate the healing of an extraction socket with and without autologous, xenogenic or alloplastic bone substitute material

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00026275
Enrollment
30
Registered
2021-10-06
Start date
2021-10-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

alveolar ridge atrophie K08.2

Interventions

Group 1: Extraction of 2 teeth per patient. The control extraction socket heals without any bone substitute material. Samples will be taken after 0, 24 and 72 hours of the clot in the extraction socke

Sponsors

Klinik- fur Mund-, Kiefer- und Gesichtschirurgie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) Patients with a minimum of 2 teeth, which are not worthy of preservation in the upper or lowe jaw followed by implantation 2) Patients with an age of legal majority and legal capacity 3) Patient is willing to participate in follow-up examinations

Exclusion criteria

Exclusion criteria: 1) Disabled persons 2) Circumstances which interfere with successful study participation or analysis of results (e.g. non-compliance, unreliability)

Design outcomes

Primary

MeasureTime frame
Number of immune cells after 0,24 and 72 hours in histological samples.

Secondary

MeasureTime frame
Evaluation o osteogenic potential after 0,24 and 72 hours in histological samples.

Countries

Germany

Contacts

Public ContactVictoria Landwehr

Klinik- fur Mund-, Kiefer- und Gesichtschirurgie

victoria.landwehr@uniklinik-freiburg.de0761/270-49160

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026