Deciphering the evolution of viral pathogens in the context of human immunity

Deciphering the evolution of viral pathogens in the context of human immunity - EIKIM

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00026266

Enrollment

300

Registered

2023-06-16

Start date

2023-08-07

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

SARS-CoV-2 infection and immunity Influenza virus infection and immunity Viral respiratory tract infections

Interventions

Group 1: Repeated blood draws and questionnaires

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Good physical condition (Karnofsky-Index =80%)

Exclusion criteria

Exclusion criteria: - <8 weeks (men)/<12 Wochen (women) since last blood draw of a volume of =500 ml - Current or planned participation in an interventional vaccine study during the duration of this study

Design outcomes

Primary

Measure	Time frame
Immunity against viral respiratory pathogens (longitudinal assessment every four months; serum/plasma antibody and neutralization titer)	—

Secondary

Measure	Time frame
Selection pressure on viral respiratory pathogens (at the end of the study; neutralizing serum/plasma activity against ciruclating viral variants)	—

Countries

Germany

Contacts

Public ContactFlorian Klein

Uniklinik Köln

florian.klein@uk-koeln.de+49 221 478 85801

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026