Skip to content

Impact of manual compression therapy on the global end-diastolic volume in critical ill patients

Impact of manual compression therapy on the global end-diastolic volume in critical ill patients - CritComp

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
DRKS
Registry ID
DRKS00026226
Enrollment
34
Registered
2021-09-17
Start date
2021-10-01
Completion date
Unknown
Last updated
2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

R60.9 R57.9

Interventions

Group 1: Manual compression and compression bandaging Group 2: No manual compression therapy nor compression bandaging.

Sponsors

Universitätsklinikum Freiburg
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Admission on the intensive care unit 2. Edema 3. Hemodynamic assesment with pulse contour analysis calibrated via transpulmonary thermodilution

Exclusion criteria

Exclusion criteria: - Absence of informed consent of the patient or the legal representative respectively. - Any contraindication to perform manual compression therapy - Hemodynamic instability defined as change in the dosage of catecholamine (Noradrenaline or Adrenaline) of more than 0,15µg/kg/min within the last 12 hours before inclusion - Age less than 18 years - Pregnancy

Design outcomes

Primary

MeasureTime frame
Change of global enddiastolic volume index (GEDI) after 15, 30, 60 minutes and 24 hours after initiation of manual compression therapy.

Secondary

MeasureTime frame
Changes of intrathoracic blood volume (ITBV), central venous pressure and extravascular lung water 15, 30, 60 minutes and 24 hours after initiation of manual compression therapy. Urine volume during 24 hours with or without manual compression therapy. Edema measured by circumference of extremity after 24 hours of manual compression therapy.

Countries

Germany

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026