R60.9 R57.9
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Admission on the intensive care unit 2. Edema 3. Hemodynamic assesment with pulse contour analysis calibrated via transpulmonary thermodilution
Exclusion criteria
Exclusion criteria: - Absence of informed consent of the patient or the legal representative respectively. - Any contraindication to perform manual compression therapy - Hemodynamic instability defined as change in the dosage of catecholamine (Noradrenaline or Adrenaline) of more than 0,15µg/kg/min within the last 12 hours before inclusion - Age less than 18 years - Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change of global enddiastolic volume index (GEDI) after 15, 30, 60 minutes and 24 hours after initiation of manual compression therapy. | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes of intrathoracic blood volume (ITBV), central venous pressure and extravascular lung water 15, 30, 60 minutes and 24 hours after initiation of manual compression therapy. Urine volume during 24 hours with or without manual compression therapy. Edema measured by circumference of extremity after 24 hours of manual compression therapy. | — |
Countries
Germany