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Influence of the dopaminergic system on motor learning

Influence of the dopaminergic system on motor learning - DaT-SCAN Learn

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00026167
Enrollment
75
Registered
2021-08-24
Start date
2021-08-20
Completion date
Unknown
Last updated
2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G20

Interventions

Group 1: Patients with suspected Parkinson's syndrome are referred by a neurologist to the University of Leipzig for a DaTSCAN examination for further clarification of Parkinson's syndrome. During thi

Sponsors

Klinik für Neurologie, Uniklinik Leipzig
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: Age between 40 and 75. Signing of informed consent. Only subjects with previous nuclear medicine examination: V.a. a parkinsonian syndrome (which led to referral to nuclear medicine for FP-CIT SPECT examination).

Exclusion criteria

Exclusion criteria: Non-consent or inability of the subject to consent to study participation; pre-existing high-dose symptomatic dopaminergic therapy (> 600 mg levodopa equivalent dose); relevant postural disorder (regular falls, propensity to fall in the so-called pull test); alcohol/drug abuse (current or history); depression (BDI > 19 points); acute psychotic symptomatology; severe previous internal disease (e.g., heart failure. e.g., heart failure) or orthopedic/rheumatologic pre-existing conditions that interfere with expenditure performance; inability to perform the experimental tasks; pregnancy; relevant daytime sleepiness (ESS >12), relevant cognitive impairment (MOCA score < 18).

Design outcomes

Primary

MeasureTime frame
Extent of motor learning in patients with Parkinson's disease compared to healthy controls.

Secondary

MeasureTime frame
Extent of learning success dependent on dopaminergic deficit in DaTScan in patients with parkinson disease.

Countries

Germany

Contacts

Public ContactChristoph Mühlberg

Neurologie Uniklinik Leipzig

Christoph.Muehlberg@medizin.uni-leipzig.de0341/9724200

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026