B97.4 J12.1 J21.0 J20.5 J21.1 J21.8 J21.9
Conditions
Interventions
Group 1: • Study arm "severe RSV LRTI" (hospitalized children)
• The patients are recruited from the patient population of the participating clinics.
• Information, examination of inclusion and exclus
Transmission of the findings to the respective study center (<24 h)
Entry of the findings by the local study team
• Study arm "any RSV infection" (children treated on an outpatient basis)
• The patients are recruited from the patient pool of the participating pediatr
the first two suitable patients in the afternoon).
• Information, examination of inclusion and exclusion criteria and obtaining the declaration of consent from the local study coordinator
• Collection
Sponsors
Medizinische Hochschule Hannover, Klinik für Pädiatrische Pneumologie, Allergologie und Neonatologie
Eligibility
Sex/Gender
All
Age
0 Months to 24 Months
Inclusion criteria
Inclusion criteria: Study arm "severe RSV LRTI" (hospitalized children) • Children aged 0-24 months • Parental consent to the study • Episode requiring hospitalization • Existence of the case definition (at least one criterion from group A and B) Inclusion criteria Group A -Fever = 38.5 ° C (rectal) or 38.0 ° C (auricular, axillary, sublingual) -Cough -Signs of rhinitis (runny nose, blocked nasal breathing) -Signs of pharyngitis (difficulty swallowing, sore throat) Inclusion criteria group B -Giemen (auscultation) -rattling noises -Tachy / dyspnea -Hypoxemia Study arm "any RSV infection" (children treated on an outpatient basis) • Children aged 0-24 months • Parental consent to the study • The case definition is available (at least one criterion from group A or B) Inclusion criteria Group A -Fever = 38.5 ° C (rectal) or 38.0 ° C (auricular, axillary, sublingual) -Cough -Signs of rhinitis (runny nose, blocked nasal breathing) -Signs of pharyngitis (difficulty swallowing, sore throat) Inclusion criteria group B -Giemen (auscultation) -rattle noises -Tachy / dyspnea -Hypoxemia
Exclusion criteria
Exclusion criteria: Study arm "severe RSV LRTI" (hospitalized children) • Child is hospitalized for> 72 hours • Participation in the study at an earlier point in time (winter half-year / current season) Study arm "any RSV infection" (children treated on an outpatient basis) • Participation in the study within the last 28 days (current season)
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Detection of other respiratory pathogens (PCR) in nasopharyngeal smear or aspirate; Clinical course of RSV infection; Socio-economic costs of RSV infections | — |
Primary
| Measure | Time frame |
|---|---|
| Detection of RSV in nasopharyngeal smear or aspirate using PCR diagnostics | — |
Countries
Germany
Outcome results
None listed