K05.3
Conditions
Interventions
Group 1: Before conventional pocket cleaning, the periodontal pockets in the experimental study group are disinfected with a diode laser (wavelength: 445 nm, power: 0.5 W, cw-mode). A 320 µm fiber is
Sponsors
Klinik für Zahnerhaltung, Parodontologie und Präventive Zahnheilkunde, Universitätsklinikum der RWTH Aachen
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Minimum age 18 years, No periodontal treatment in the last two years, Generalized periodontitis up to stage 3 and grade B, Written informed consent
Exclusion criteria
Exclusion criteria: Patients who have already received periodontal treatment within the last two years, Pregnancy, Tobacco use, Dental implants, Metabolic disease with possible influence on the healing process, especially diabetes, Patients with infectious diseases, such as HIV, Hep B or Hep C, Patients undergoing chemotherapy, Patients with cystic fibrosis, Antibiosis in the last 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of periodontologically significant bacteria in the pockets (detection by qPCR for various lead bacteria and additional culture for P. gingivalis), clinical attachment level | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction of periodontologically significant bacteria in the blood, reduction of the acute phase reaction (esp. immunological parameters such as CRP, IL-6, TNF-a), periodontal recessions, probing depths, bleeding on probing (BOP), pain sensation during treatment, body temperature after treatment | — |
Countries
Germany
Contacts
Public ContactPatrick Jansen
Klinik für Zahnerhaltung, Parodontologie und Präventive Zahnheilkunde, Universitätsklinikum der RWTH Aachen
Outcome results
None listed