Allulose biokinetic in blood and urine
Conditions
Interventions
Group 1: no allulose 0g/kg body weight (BW)
Group 2: 0,2 g/kg BW Allulose
Group 3: 0,4 g/kg BW Allulose
Sponsors
Max Rubner-Institut Bundesforschungsinstitut für Ernährung und Lebensmittel
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: -Healthy women and men - BMI 18.5 - 30 kg/m2 - informed written consent - good metabolic health - no dietary sensitivities e.g fructose malabsorption, IBD... - normal range parameters for liver and kidney function, blood lipids, inflammation markers (screening blood sample) - non-smokers - no chronic intake of medication (except hormonal contraceptives) - no intake of antibiotics in the prior 6 months - no pregnancy or lactation phase - no known allergies against components of the study foods
Exclusion criteria
Exclusion criteria: see inclusion criteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Allulose concentration (mg/dl) in plasma at t=2h after allulose consumption Excreted amount of allulose (g) in urine in the 12h after allulose consumption | — |
Secondary
| Measure | Time frame |
|---|---|
| Anthropometric data Plasma - glucose, lactate, insulin Blood lipids, fasting and late postprandal (LDL-C; HDL-C; TG; apoB, apoCIII, apoA1) microbiome composition in urine Allulose in saliva at baseline and 1h and 4h after allulose consumption Allulose Cmax, tmax and AUC in plasma and urine | — |
Countries
Germany
Contacts
Public ContactMaria Herrmann
Max Rubner-Institut, Bundesforschungsinstitut für Ernährung und Lebensmittel, Institut für Physiologie und Biochemie der Ernährung
Outcome results
None listed