Prospective clinical investigation of the effects of bariatric surgery on nocturnal hypoxaemic burden in patients with severe obesity

Prospective clinical investigation of the effects of bariatric surgery on nocturnal hypoxaemic burden in patients with severe obesity - BASH

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00026004

Enrollment

100

Registered

2021-08-19

Start date

2020-01-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

E66.02 G47.9

Interventions

Group 1: Patients with morbid obesity and the associated indication for bariatric surgery The following examinations are carried out preoperatively and 6 months postoperatively: Cardiorespiratory p

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Indication for bariatric surgery according to the S3 guideline: Surgery of obesity and metabolic diseases The patient is fully informed and agrees to participate in the study The surgical indication has been secured by a multidisciplinary team consisting of a nutritionist, surgeon, psychosomatic specialist / psychologist and, if necessary a general doctor.

Exclusion criteria

Exclusion criteria: Consent to participate in the study has not been given or will be revoked. Bariatric surgery is not performed. Previously known severe chronic respiratory failure requiring oxygen therapy General inoperability Contraindication to bariatric surgery according to the S3 guideline: Surgery for obesity and metabolic diseases: - Unstable psychopathological conditions, untreated bulimia nervosa, active substance dependence - Consuming underlying diseases, malignant neoplasms, untreated endocrine causes, chronic diseases worsened by a postoperative catabolic metabolism - Present or planned pregnancy

Design outcomes

Primary

Measure	Time frame
Nocturnal hypoxaemic burden preoperativly and six month postoperatively	—

Secondary

Measure	Time frame
Weight loss Apnea / Hypopnea Index (AHI) Static and dynamic lung volumes (vital capacity, inspiratory capacity, expiratory reserve volume, forced one-second capacity (FEV1)) Systolic and diastolic cardiac function (morphology, global longitudinal Strain) Parameters of the acid-base balance (blood pH, carbon dioxide partial pressure, Standard bicarbonate and base excess) Characterization of daytime sleepiness	—

Measure

Time frame

Weight loss Apnea / Hypopnea Index (AHI) Static and dynamic lung volumes (vital capacity, inspiratory capacity, expiratory reserve volume, forced one-second capacity (FEV1)) Systolic and diastolic cardiac function (morphology, global longitudinal Strain) Parameters of the acid-base balance (blood pH, carbon dioxide partial pressure, Standard bicarbonate and base excess) Characterization of daytime sleepiness

—

Countries

Germany

Contacts

Public ContactBarbara Jacobi

Klinikum Saarbrücken

bjacobi@klinikum-saarbruecken.de06819632447

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026