To investigate neurohistomorphological changes of the colon and rectal wall and their genesis in patients with a bowel evacuation disorder in the sense of an intestinal transit disorder expulsion disorder

To investigate neurohistomorphological changes of the colon and rectal wall and their genesis in patients with a bowel evacuation disorder in the sense of an intestinal transit disorder expulsion disorder - Neuropathological changes of the intestinal wall in patients with bowel evacuation disorder

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00025977

Enrollment

500

Registered

2021-08-02

Start date

2019-03-19

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K59.01

Interventions

Group 1: Patients are questioned with score questionnaires stool habits (Wexner, Altomare, Rectal Toxicity, CACP) and quality of life (PHQ-9, GAD-7). The results of neuropathologic examinations and de

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Consent, surgery with bowel resection, presence of bowel dysfunction, exclusion of colorectal carcinoma, age > 18 years.

Exclusion criteria

Exclusion criteria: Age < 18 years, lack of informed consent, no bowel resection planned, underlying malignancy, lack of functional bowel dysfunction

Design outcomes

Primary

Measure	Time frame
Pathohistomorphological changes of the bowel wall associated with clinical observations.	—

Secondary

Measure	Time frame
Clinical scores after surgery	—

Countries

Germany

Contacts

Public ContactClaudia Rudroff

Klinik für Allgemein- und Viszeralchirurgie EVK Köln Weyertal

claudia@rudroff.com+49-221-4795110

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 7, 2026