F32 F33
Conditions
Interventions
Group 1: The course of body weight and symptoms will be observed over four weeks after the start of medicinal antidepressant treatment in a group of patients with secured diagnosis of depression.
Sponsors
Klinikum der Universität München, Campus Großhadern
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: - diagnosis of a current depressive episode (ICD-10: F32.x) or recurrent depression (ICD-10: F33.x) - male and female psychiatric inpatients aged between 18 and 70 years - ability to sufficiently speak and comprehend the German language - continuing or beginning antidepressant drug regimen within two weeks after admission - MADRS score = 14 - capability of providing written informed consent or in agreement with a legal representative.
Exclusion criteria
Exclusion criteria: - cognitive disability impeding completion of self-rating questionnaires or answering questions reasonably; - presence of psychotic features, manic episode, bipolar disorder, disorders from the schizophreniform spectrum, eating disorder, drug or alcohol addiction. Other disorders (e.g. adjustment disorder, obsessive compulsive disorder, anxiety disorder, somatoform disorder, personality disorder) in case the symptoms predominate the clinical picture; - presence of uncontrolled systemic disease, uncontrolled somatic (other than metabolic or cardiovascular disturbances) / neurological disorder (apart from migraine), current or recent (last month) severe infections or inflammatory disease, current or recent (last month) physical trauma; - treatment with ECT; - patients with immediate risk for suicidal behavior; - pregnant, breast-feeding, or postmenopausal women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| body weight change after 4 weeks (neasurement of body weight), symptom score change after 4 weeks (MADRS score) | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlations of relevant biomarkers and patient characteristics | — |
Countries
Germany
Contacts
Public ContactMaria Simon
Klinik für Psychiatrie und Psychotherapie, Klinikum der Universität München, Ludwig-Maximilians-Universität München
Outcome results
None listed