Experimental clinical trial on recalibration and realignment during prism adaptation training for treating visual neglect

Experimental clinical trial on recalibration and realignment during prism adaptation training for treating visual neglect - PANREX

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00025938

Enrollment

Registered

2021-09-30

Start date

2021-11-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

R29.5

Interventions

Group 1: Arm 1: general neglect treatment (30 minutes). It will take place on the first day oft he study (after the neuropsychological assessment) and will not be randomized. Patients receive a simple

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - minimal age: 18 years - left-sided neglect after right hemisphreic lesion (based on neuropsychological assessment) - sufficient capacity to participate in the treatment (40 minutes) - sufficient capability to be mobilized into the wheelchair on all 5 days

Exclusion criteria

Exclusion criteria: - premorbid dementia - normal pressure hydrocephalus - prior traumatic brain injury

Design outcomes

Primary

Measure	Time frame
Aim: to recruit at least 23 patients. The primary outcome parameter is the reaction time from the CSA (in ms).	—

Secondary

Measure	Time frame
Further secondary outcome parameters (gathered by the neuropsychological assessment prior to inclusion to the study) are: - Apples Cancellation Test - Line crossing (Neglect-Test) - Line Bisection (Neglect-Test) - Clock Drawing Test - Baking-Tray Task (blinded) - Sitting position (spontaneously and after cueing, blinded) - Evaluations of activities of daily living (Barthel-Index and Catherine Bergego Scale, each blinded) - Standardized fingerperimetric examination - Evaluation of further sensory, motor and representational neglect domains (tactile, acoustic and representational neglect) During the treatment we will assess the after-effect with a mask (in cm): deviation of the experienced body midline (by means of straight ahead pointing with eyes closed) from the real midline. We will calculate the difference between experienced body midline before and after the treatment.	—

Measure

Time frame

Further secondary outcome parameters (gathered by the neuropsychological assessment prior to inclusion to the study) are: - Apples Cancellation Test - Line crossing (Neglect-Test) - Line Bisection (Neglect-Test) - Clock Drawing Test - Baking-Tray Task (blinded) - Sitting position (spontaneously and after cueing, blinded) - Evaluations of activities of daily living (Barthel-Index and Catherine Bergego Scale, each blinded) - Standardized fingerperimetric examination - Evaluation of further sensory, motor and representational neglect domains (tactile, acoustic and representational neglect) During the treatment we will assess the after-effect with a mask (in cm): deviation of the experienced body midline (by means of straight ahead pointing with eyes closed) from the real midline. We will calculate the difference between experienced body midline before and after the treatment.

—

Countries

Germany

Contacts

Public ContactJannik Scheffels

Krankenhaus Lindenbrunn

j.scheffels@krankenhaus-lindenbrunn.de+49 5156 782 799

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 7, 2026