Kinetics of various routine paraclinical parameters (triiodothyronine, L-thyroxine, thyroxine-binding globulin, bilirubin) during hemoadsorption with CytoSorb® with special consideration of the adsorber saturation kinetics.

Kinetics of various routine paraclinical parameters (triiodothyronine, L-thyroxine, thyroxine-binding globulin, bilirubin) during hemoadsorption with CytoSorb® with special consideration of the adsorber saturation kinetics. - CytoSoFTT34

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00025926

Enrollment

Registered

2021-08-04

Start date

2023-10-05

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemoadsorption R57.2

Interventions

Group 1: Intensive care patients in septic shock under hemoadsorption. Blood samples will be taken at baseline, 60, 120, 240, 480 minutes after and 60 minutes before adsorber change. Concentrations of

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. intensive care patients with septic shock 2. indication for adjunctive hemoadsorption

Exclusion criteria

Exclusion criteria: 1. pregnant, postpartal or breast-feeding patients 2. patients with known thryroid disease 3. known pituitary disease 4. known thalamus disease

Design outcomes

Primary

Measure	Time frame
Concentration of triiodothyronine, thyroxine and thyroxine-binding globulin in the blood at the different time points during CytoSorb treatment.	—

Secondary

Measure	Time frame
Concentration of bilirubin in the blood at the different time points during CytoSorb treatment.	—

Countries

Germany

Contacts

Public ContactDietrich Henzler

Universitätsklinik für Anästhesiologie, operative Intensivmedizin, Rettungsmedizin, Schmerztherapie, Campus OWL, Klinikum Herford AöR

dietrich.henzler@klinikum-herford.de+49 (0)5221 94 2481

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026