G31.9
Conditions
Interventions
Group 1: In addition to their clinically indicated PET/MR examination (Biograph mMR, Siemens, Germany) of the brain, patients receive a head examination in a PET head scanner (CareMiBrain, Oncovision,
Sponsors
Oncovision(GENERAL EQUIPMENT FOR MEDICAL IMAGING S.A.)
Eligibility
Sex/Gender
All
Age
21 Years to 99 Years
Inclusion criteria
Inclusion criteria: Age =21 years, Mini Mental Status Test (MMST) > 20, clinical indication for a PET/MRI brain examination due to a neurodegenerative disease, contraception in patients of childbearing potential, written consent.
Exclusion criteria
Exclusion criteria: Pregnant and breastfeeding women, underage patients, limited ability of the patient to give consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Qualitative and quantitative comparison of PET data sets from a brain PET scanner (CareMiBrain) with diagnostic PET data sets from PET/MRT (Biograph mMR). The aim is to show the "non-inferiority" of the dedicated brain PET imaging to the clinical standard (PET in the context of PET/MR imaging). | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation improvement of the attenuation correction algorithms, optimization of the PET acquisition parameters (reduction of acquisition times), possibility of dose reduction based on simulation calculations, workflow optimization, evaluation of the potential time savings through the use of the PET-only scanner, evaluation of patient comfort. | — |
Countries
Germany
Contacts
Public ContactChristian la Fougère
Universitätsklinikum Tübingen, Radiologische Klinik, Nuklearmedizin & Klinische Molekulare Bildgebung
Outcome results
None listed