Pain and Pain Treatment
Conditions
Interventions
Group 1: Using a sham Brain-Computer-Interface a placebo will be induced (expectation towards a brain state of low pain susceptibility). 30 trials per measurement. In pseudorandomized order with Arm 2
Sponsors
Universitätsklinikum Hamburg-Eppendorf
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Healthy adults with normal or corrected-to-normal vision, right-handed
Exclusion criteria
Exclusion criteria: - any contraindications for MRI measurement (metal implants, non-removable piercings, heart pacemaker, tattoos close to the head, known claustrophobia) - red-green deficiency - chronic or acute disease or pain - neurological or psychiatric disorders - pregnancy - regular medication intake (except contraceptive), recent use of psychotropic or analgesic substances - use of illegal drugs - consumption of caffeine 2 hours before MRI testing and consumption of alcohol on the day of testing and the previous day - smoking - participation in any medication-associated experimental study in the last 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Our aim is to assess time-frequency (EEG) and spatial (fMRI) neural characteristics of positive and negative expectations on pain in the expectation phase prior to the application of painful stimuli. | — |
Secondary
| Measure | Time frame |
|---|---|
| In addition, we will examine the neural processes after the cue presentation and after the application of the pain stimuli. | — |
Countries
Germany
Contacts
Public ContactMaren-Isabel;Christoph Wolf;Wittkamp
Universitätsklinikum Hamburg-Eppendorf, Institut für systemische Neurowissenschaften;Universitätsklinikum Hamburg-Eppendorf, Institut für systemische Neurowissenschaften
Outcome results
None listed