Investigation of the effect of an acetylsalicylic acid infusion on the arachidonic acid metabolism in the blood plasma and urine of healthy male volunteers

Investigation of the effect of an acetylsalicylic acid infusion on the arachidonic acid metabolism in the blood plasma and urine of healthy male volunteers - ASAPUFA

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00025848

Enrollment

Registered

2021-07-26

Start date

2018-05-10

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers

Interventions

Group 1: one-time Acetylsalicylic acid 500mg intravenous dissolved and injected in 100ml sodium chloride 0,9% Group 2: one-time 100 ml sodium chloride 0,9% intravenous

Eligibility

Sex/Gender

Male

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: no relevant pre-existing conditions

Exclusion criteria

Exclusion criteria: medication intake

Design outcomes

Primary

Measure	Time frame
ASA-related changes in plasma and urine concentrations of polyunsaturated fatty acids, in particular arachidonic acid derivatives	—

Secondary

Measure	Time frame
diurnal changes of polyunsaturated fatty acids / arachidonic acid derivatives	—

Countries

Germany

Contacts

Public ContactMarc Revermann

Klinik für Anästhesiologie und Operative IntensivmedizinUniversitätsklinikum Mannheim

marc.revermann@umm.de0621 383 3536

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026