Survival of molars with degree III periodontal furcation involvement following non-surgical or surgical therapy: a multicentre single-masked randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00025830

Enrollment

135

Registered

2021-07-21

Start date

2022-05-11

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K05.3

Interventions

Group 1: nonsurgical subgingival instrumentation of molars with class III furcation involvement Group 2: surgical subgingival instrumentation (access flap) of molars with class III furcation involveme

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: · Minimum of 12 teeth present · Diagnosis of Severe Periodontitis stage III or IV · at least one maxillary/ mandibular molar with: i) degree III horizontal furcation involvement (at least between 2 roots for maxillary molars) (Eickholz and Walter, 2018), ii) class B vertical furcation involvement (bone loss up to the middle third of root cones) (Tonetti et al. 2017), iii) residual probing pocket depths > 5 mm and iv) maximum mobility degree I (Miller et al. 1985) · Received a course of non-surgical periodontal therapy within the past six months

Exclusion criteria

Exclusion criteria: · Full mouth plaque score > 30% · A course of antibiotics within the past 3 months · Pregnant/lactating women · Relevant medical history as evaluated by the examining clinician which may have the potential to affect periodontal surgical treatment · Individuals on long-standing (2 or above years) supportive periodontal therapy (SPT) management plans

Design outcomes

Primary

Measure	Time frame
Tooth survival 5 years after treatment	—

Secondary

Measure	Time frame
Max PPD (tooth level) Max CAL (tooth level) Radiographic bone levels (tooth level) Oral-health-related quality of life (OHrQL) measures Time needed for each study appointment during maintenance therapy Health economics (cost-effectiveness and cost-utility, cost-effectiveness-acceptability) Occurrence of root caries in furcation area (yes/no) Any measure for dentin hypersensitivity? Subgingival microbial changes 1- and 3-year tooth survival	—

Measure

Time frame

Max PPD (tooth level) Max CAL (tooth level) Radiographic bone levels (tooth level) Oral-health-related quality of life (OHrQL) measures Time needed for each study appointment during maintenance therapy Health economics (cost-effectiveness and cost-utility, cost-effectiveness-acceptability) Occurrence of root caries in furcation area (yes/no) Any measure for dentin hypersensitivity? Subgingival microbial changes 1- and 3-year tooth survival

—

Countries

Germany, Italy, Spain, Sweden, United Kingdom

Contacts

Public ContactPeter Eickholz

Poliklinik für Parodontologie, ZZMK der Johann Wolfgang Goethe- Universität

eickholz@med.uni-frankfurt.de06963015642

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 9, 2026