Soft tissue dimensional changes of augmented and non-augmented human extraction sockets: A prospective study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00025812

Enrollment

Registered

2021-07-13

Start date

2021-07-01

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K08.2

Interventions

Group 1: extraction sockets will be augmented with porcine grafting material (MinerOss® XP) Group 2: extraction sockets will be not (control) augmented

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: medical indication for the surgical removal of teeth

Exclusion criteria

Exclusion criteria: unsigned consent

Design outcomes

Primary

Measure	Time frame
At 2, 4, 6, 8 and 12 weeks impressions with irreversible hydrocolloide will be taken and the stone casts digitized. The horizontal and vertical changes will be compared between augmented and non-augmented sites using Meshlab and calculated with the Haussdorff distance algorithm. The two-factorial nonparametric analysis is used to deetermine the influence of independent factor (augmentation) on the dimensional changes as well as the interaction effect for the variables time and augmentation.	—

Measure

Time frame

At 2, 4, 6, 8 and 12 weeks impressions with irreversible hydrocolloide will be taken and the stone casts digitized. The horizontal and vertical changes will be compared between augmented and non-augmented sites using Meshlab and calculated with the Haussdorff distance algorithm. The two-factorial nonparametric analysis is used to deetermine the influence of independent factor (augmentation) on the dimensional changes as well as the interaction effect for the variables time and augmentation.

—

Secondary

Measure	Time frame
histomorphometric and immunohistochemical analysis of a bone biopsy	—

Countries

Germany

Contacts

Public ContactSusanne Nahles

Charité CVK Klinik für MKG-Chirurgie

susanne.nahles@charite.de030450555022

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 7, 2026