F17.2
Conditions
Interventions
Group 1: Intervention: Smoking Avatar
Duration: about 20 minutes.
Group 2: Control: Non-Smoking Avatar
Duration: about 20 minutes.
Sponsors
Zentralinstitut für Seelische Gesundheit (ZI)
Eligibility
Sex/Gender
Male
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Male sex, tobacco smoker.
Exclusion criteria
Exclusion criteria: Psychiatric comorbidity with psychiatric or psychotherapeutic treatment in the past 10 years (>1 psychiatric or psychotherapeutic treatment). Severe physical disease: cancer treatment during the past 10 years; metabolic disease (Addison's disease, Cushing's disease, hypogonadism, testosterone treatment); neurological disease (multiple sclerosis, Parkinson's disease, amyotrophic lateropathy, stroke during the past 5 years, traumatic brain disease with persistent neurological deficit); acute cardiovascular disease (first manifestation during the past 4 weeks), myocardial infarction, decompensated cardiac insufficiency; renal insufficiency; infectious disease currently being treated; rheumatological disease. Current use of medications for mental illness or use of drugs that interact with the central nervous system within a maximum of 5 half-lives. Known intolerance to high frequency flickering visual stimuli, as seen in very rare cases in certain forms of epilepsy (ascertainable through reported similar problems in past movie theater visits). Abstinence from cigarettes < 12 hours before planned study inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Explicit craving for smoking, implicit wanting of cigarette smoking (Implicit Association Test), approach behavior towards cigarette stimuli (Approach-Avoidance Test), selective attention toward cigarette stimuli (Dot-Probe Test) measured on three different occasions (smoking avatar vs non-smoking avatar; additionally: without an avatar). | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxytocin, arginine-vasopressin, cortisol, and alpha-amylase in plasma and saliva on the following test conditions: smoking avatar vs non-smokign avatar; additionally without an avatar, before and after smoking. | — |
Countries
Germany
Contacts
Public ContactKatharina Eidenmüller
Zentralinstitut für Seelische Gesundheit (ZI)
Outcome results
None listed