T70
Conditions
Interventions
Group 1: Sleep for one night in a 30 ° upright body position in a normobaric hypoxic atmosphere with 13.5% oxygen
Group 2: Sleep for one night in horizontal body position in a normobaric hypoxic atmo
Sponsors
Deutsches Zentrum für Luft- und Raumfahrt (DLR)Institut für Luft- und Raumfahrtmedizin Abteilung Kardiovaskuläre Luft- und Raumfahrtmedizin (KLM)
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: women and men = 18 years of age regular weight (BMI 18,5 - 29) lowlanders caucasians
Exclusion criteria
Exclusion criteria: Chronic medical conditions (COPD, obstructive sleep apnea, heart failure) Sleep related disease (sleep disturbance), shift workers Smoking Altitude exposure >3000 m within the last 3 months Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effect of posture during one night at 13.5% O2 on normobaric hypoxia 1) the peripheral oxygen saturation measured continuously on the finger during sleep. The course of oxygen saturation in a horizontal and upright sleeping position are compared. 2) on the cognitive function, in particular the parameters "speed" and "accuracy" in the COGNITION test battery. The cognitive performance in the morning after the horizontal and the upright sleeping position are compared. | — |
Secondary
| Measure | Time frame |
|---|---|
| Alterations in cerebral water diffusion by diffusion weighted cerebral MRI | — |
Countries
Germany
Contacts
Public ContactUlrich Limper
Deutsches Zentrum für Luft- und Raumfahrt (DLR)Institut für Luft- und Raumfahrtmedizin Abteilung Kardiovaskuläre Luft- und Raumfahrtmedizin (KLM)
Outcome results
None listed