D43.0 C71
Conditions
Interventions
Group 1: nTMS and DTi-based neuronavigation with subsequent tumor resection
Sponsors
Klinik für Neurochirurgie Klinikum Nürnberg Paracelsus Medizinische Privatuniversität
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: supratentorial location of the tumor language eloquent tumor or patient has language impairment proposed entity: primary or secondary brain tumor all lesions of that patient are treated surgically Mini Mental Status Examination >= 20 points
Exclusion criteria
Exclusion criteria: patients not eligible for MRI patients with CSF fluid diversion patients with implanted devices for neuromodulation or deep brain stimulation patients who cannot consent patient refuses participation pregnant or breast-feeding patients patients with exclusively infratentorial lesions patients with meningiomas as lesion to be treated patients on dialysis patients with coronary heart disease patients with heart rhythm disorders (except AV-block °I) patients with NYHA III and NYHA IV heart failure patients not eligible for nTMS language testing in German language patients not eligible for nTMs language testing due to high grade of aphasia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of tumor resection | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative tumor volume (cm³) on postoperative MRI (24-72hrs postoperative) postoperative langugae function (Token Test) postoperative day 2, before discharge, at follow-up after 3-6 months postoperative neurologic status (NIHSS) postoperative day 2, before discharge, at follow-up after 3-6 months predictive value of nTMS-examinations for postoperative neurologic outcome | — |
Countries
Germany
Contacts
Public ContactThomas Eibl
Klinik für Neurochirurgie Klinikum Nürnberg Paracelsus Medizinische Privatuniversität
Outcome results
None listed