The effect of framing and communicating COVID-19 vaccine side-effect risks on vaccine intentions: a randomized controlled trial

The effect of framing and communicating COVID-19 vaccine side-effect risks on vaccine intentions: a randomized controlled trial - CovidRisk

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00025551

Enrollment

12000

Registered

2021-07-12

Start date

2021-07-25

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19 vaccine use intentions

Interventions

Group 1: Status-quo arm: This arm will be used as a secondary analysis to determine how the status-quo framing of vaccine side effects (how they were actually presented to individuals by the media) co

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Above the age of 18 2. Speak English 3. Live in the United States or United Kingdom

Exclusion criteria

Exclusion criteria: Exclusion criteria for all data collection are those who do not meet the above-listed inclusion criteria.

Design outcomes

Primary

Measure	Time frame
Individuals' stated willingness to take the hypothetical COVID-19 vaccine measured using a 4 point Likert scale (no, unsure leaning towards no, unsure leaning towards yes, yes).	—

Secondary

Measure	Time frame
Individuals' perception of the safety of the hypothetical COVID-19 vaccine measured on a 10 point scale ranging from 1 (extremely unsafe) to 10 (extremely safe).	—

Countries

United Kingdom, United States

Contacts

Public ContactNikkil Sudharsanan

Heidelberg Institute of Global Health, Heidelberg University

nikkil.sudharsanan@uni-heidelberg.de6221 56-8035

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 21, 2026