Transcutaneous vagal nerve stimulation to improve cognitive control in patients with Parkinson’s disease

Transcutaneous vagal nerve stimulation to improve cognitive control in patients with Parkinson’s disease - T-VNS is Parkinson's disease

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00025548

Enrollment

Registered

2021-08-26

Start date

2021-10-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G20

Interventions

Group 1: active stimulation for the duration of the Go-NoGo-Change Task Group 2: sham stimulation for the duration of the Go-NoGo-Change Task

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Diagnosis Morbus Parkinson

Exclusion criteria

Exclusion criteria: Dementia (MMST Score <20), diagnosis of other neurological or psychiatric disorders, patients using medication that affect pupillary reflexes, pregnancy

Design outcomes

Primary

Measure	Time frame
Accuracy- and Reaction TIme Data of the Go-NoGo-Change task	—

Secondary

Measure	Time frame
tVNS modulation effect on mid-frontal theta activity during Go-No-Go-Change task performance; Pupil-dilation and blood pressure difference before and after stimulation	—

Countries

Germany

Contacts

Public ContactKathrin Janitzky

Universitätsklinik für Neurologie, Evangelisches Krankenhaus Oldenburg Neurologie, Fakultät für Medizin und Gesundheitswissenschaften, Carl von Ossietzky Universität Oldenburg

Kathrin.Janitzky@uni-oldenburg.de+49 (0)441/ 236-649

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026