Ventilation – Perfusion mismatch in COVID-19 as a potential cause for hypoxemia - a pathyphysioloigcal study

Ventilation – Perfusion mismatch in COVID-19 as a potential cause for hypoxemia - a pathyphysioloigcal study - VentPerf

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00025503

Enrollment

Registered

2021-06-23

Start date

2021-10-13

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ARDS from COVID-19

Interventions

Group 1: 13 COVID-19 patients within the 1 week from the intubation will undergo: 1) MIGET: 6 inert gases (SF6, Ethane, Cyclopropane, Isoflurane, Ether und Acetone) dissolved in normal saline will be

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: - ARDS from COVID-19 - Within 1 week from the Intubation

Exclusion criteria

Exclusion criteria: - Allergy to the radiological contrast - Hepatic Cirrhosis - ECMO/ECCO2R - Patent foramen ovale

Design outcomes

Primary

Measure	Time frame
We want to show that the functional (as evaluated by MIGET) and anatomical (as evaluated by DECT) features of COVID-19 ARDS are dissociated.	—

Secondary

Measure	Time frame
The evolution of the causes of hypoxemia with passing time.	—

Countries

Germany

Contacts

Public ContactOnnen Mörer

Anästhesie

omoerer@gwdg.de+495513967744

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026