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Association of frailty phenotypes with peri-/postoperative outcomes and gene expression in older patients with cardiovascular diseases.

Association of frailty phenotypes with peri-/postoperative outcomes and gene expression in older patients with cardiovascular diseases. - FrACoG

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00025449
Enrollment
80
Registered
2021-06-07
Start date
2021-06-06
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing cardiac surgery or elective transchateter aortic valve intervention (TAVI)

Interventions

Group 1: Patients undergoing elective heart surgery or intervention (TAVI) of = 70 years. Immediately after the routine examinations (hospital admission), the following tests, which are not part of th
Katz index) - Instrumental Activity of Daily Living (IADL
Lawton Index) - Mini Nutritional Assessment short form (MNA-SF) - Mini-Mental State Examination (MMSE) - Cardiac anxiety questionnaire (HAF-17) - Health questionnaire for patients (PHQ-9) - Quality of

Sponsors

Professur für Rehabilitationsmedizin, Fakultät für Gesundheitwissenschaften Brandenburg an der Universität Potsdam
Lead Sponsor

Eligibility

Sex/Gender
All
Age
70 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients undergoing elective heart surgery or intervention (TAVI), age = 70 years

Exclusion criteria

Exclusion criteria: Severe cognitive impairment (e.g. diagnosed dementia) Clinical instability (e.g. unstable vital signs), Dialysis, Liver cirrhosis, Untreated cancer or life expectancy <1 year, Oxygen demand (at home), Need for emergency surgery / intervention, Language barrier, Patient's withdrawal

Design outcomes

Primary

MeasureTime frame
Mortality or major morbidity

Secondary

MeasureTime frame
Myocardial infarction, Atrial fibrillation, Bleeding, Blood transfusion, Vascular complications (access point / access-related complications), Lung infection, Acute respiratory distress syndrome (ARDS), Length of stay (date; intensive care unit; hospital), Intra-aortic balloon pump (IABP), Pericardial effusion (need for treatment), Delirium (need for drug treatment) Gene expression muscles (quantitative), Discharge to care facility or similar, Quality of life

Countries

Germany

Contacts

Public ContactSimon Sündermann

Charité – Universitätsmedizin Berlin Klinik für Kardiovaskuläre Chirurgie

simon.suendermann@charite.de+49 (0)30 450 665841

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026