healthy subjects
Conditions
Interventions
Group 1: Participants (n = 50).
In a repeated-measures design, the pupillary light reflex of each subject is measured at 4 study visits:
T0: Baseline measurement.
T1: Measurement after 24h sleep depr
Sponsors
Stellar DBS GmbH
Eligibility
Sex/Gender
All
Age
18 Years to 68 Years
Inclusion criteria
Inclusion criteria: Healthy participants of ages between 18 und 68 years.
Exclusion criteria
Exclusion criteria: Epilepsy, neurological diseases (e.g. appoplexy, cerebral hemorrhage, neurodegenerative diseases). Severe eye disease (e.g. glaucoma, retinal detachment, pupillary motor disorder). Mental illness. Metabolic diseases. Medication that affects the pupillary motor function and the sympathetic or parasympathetic nervous system. Medication that affects the ability to concentrate (e.g. painkillers from level II according to WHO). Drug/alcohol abuse. Visible head injuries or diseases in the area of the head. Artificial eye lenses or absence of an eye lens. To ensure optimal concentration, participants should also refrain from drinking excessive amounts of coffee or tea for 24 hours prior to testing, as well as do not engage in extreme sports.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The aim is to show that the pupillary light reflex parameters exhibit a condition-specific pattern in the 3 stages of the repeated-measures design (control condition, alcohol ingestion, sleep deprivation). The 4th test of the diurnal profiles is designed to determine the background noise that occurs within a subject over the course of a day. | — |
Secondary
| Measure | Time frame |
|---|---|
| Acceptance of measurement. | — |
Countries
Germany
Outcome results
None listed