INFLAMMATION metabolism
Conditions
Interventions
Group 1: vegan diet
Group 2: omnivor diet
Sponsors
Charité Campus Virchow-Klinikum
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: - Age = 65 to 80 years - MMSE = 24 points - No severe cardiac (up to NYHA II) and renal insufficiency (GFR> 30 ml / min) - no liver insufficiency and - cirrhosis - No severe COPD (stages I to II) - No tumor diseases
Exclusion criteria
Exclusion criteria: - Age 80 years - MMSE <24 - BMI <22 kg / m² and BMI = 30 kg / m² - Special diets (vegetarian, vegan, low-carbohydrate / ketogenic, weight reduction programs, forms of fasting) - Unintentional weight loss in the last six months (= 5%) - food allergies - Severe cardiac (from NYHA III) or renal insufficiency (GFR <30 ml / min) - Liver insufficiency and liver cirrhosis (Child Pugh Score A - C) - Severe COPD (stage III to IV) - Existing oncological disease - Diabetes mellitus requiring treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Significant differences in triglyceride concentrations in blood serum in the intervention group of 0.65 mmol / l and in the control group of 1.025 mmol / l after 48 hours of vegan diet modification. | — |
Secondary
| Measure | Time frame |
|---|---|
| Short-term vegan nutritional intervention can reduce the pro-inflammatory status in healthy, older subjects. | — |
Countries
Germany
Contacts
Public ContactKristina Norman
Charité - Universitätsmedizin Berlin Forschungsgruppe Geriatrie
Outcome results
None listed