Retrospective study of the influence of hyponatremia on bone quality and fractures due to low-energy trauma measured by QCT

Retrospective study of the influence of hyponatremia on bone quality and fractures due to low-energy trauma measured by QCT - Bone quality measured by QCT

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00025416

Enrollment

220

Registered

2021-06-07

Start date

2021-05-27

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

S32.0 S32.0

Interventions

Group 1: Sixty-eight patients with vertebral body fracture (mean age: 64¬.16 ± 18.24

31 women and 37 men) due to low-energy trauma were treated at the university hospital within 1 year and included in the study. Chronic hyponatremia was defined as serum sodium < 135 mmol/l at admissio

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: - Patients with low-energy trauma and fractures in the lumbar spine who were followed-up at UMG and had both osteoporosis and chronic hyponatremia - Control patient population with high-energy trauma and fractures or injuries to the lumbar spine.

Exclusion criteria

Exclusion criteria: - Patients with tumor diseases - Patients with pathological fractures - Implantations in the area of the spine (previous operations)

Design outcomes

Primary

Measure	Time frame
Possible influence of hyponatremia on bone quality.	—

Secondary

Measure	Time frame
Bone quality measured by QCT analysis.	—

Countries

Germany

Contacts

Public ContactWolfgang Lehmann

UMGAbteilung: CUOP

wolfgang.lehmann@med.uni-goettingen.de0551/39-22462

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026