K90.3
Conditions
Interventions
Group 1: All patients undergoing a partial pancreatectomy will be screened for an EPI to determine the postoperativ EPI-incidence.
Group 2: In a second group of patients, already receiving PERT, the
Sponsors
Klinik für Allgemein-, Viszeral- und Thoraxchirurgie Universitätsklinikum Hamburg-Eppendorf 20246 Hamburg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - surgical procedure: partial pancreatectomy - status EPI preoperative: no EPI - individual patient characteristics: sufficient patient adherence to follow-up
Exclusion criteria
Exclusion criteria: Complicated post-operative course (prolonged stay in the intensive care unit and necessity of reoperation).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Incidence of newly developed postoperative organic EPI based on the quantitative determination of fecal elastase (pre- and postoperative determination of fecal elastase) 2. Incidence of newly developed postoperative functional EPI based on cardinal symptoms and further diagnostics (standardized questionnaire for assessment of symptoms) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Reduction in quality of life due to pancreatic enzymes replacement therapy (standardized questionnaire to assess willingness to pay) 2. Monetary cost of pancreatic enzyme replacement therapy (questionnaire to assess average daily doses of pancreatic enzymes, known cost of pancreatic enzyme capsules) 3. Monetary cost of EPI-screening (laboratory cost and postage price) | — |
Countries
Germany
Contacts
Public ContactLouisa Stern
Klinik und Poliklinik für Allgemein-, Viszeral- und ThoraxchirurgieUniversitätsklinikum Hamburg-Eppendorf
Outcome results
None listed