U09.9 Post-COVID 19 condition, unspecified
Conditions
Interventions
Group 1: - fraction of symptomatic patients at timepoints 6, 9, 12, 24 months after acute COVID-19
- course of symptoms over time
- predictive and prognostic factors (sex, age, severity of acute COVID
Sponsors
InfektiologieKlinik für Innere Medizin II/Universitätsklinikum Freiburg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - patients with confirmed COVID-19 (SARS-CoV2+ PCR in respiratory, blood or faecal sample); - patients with anti-SARS-CoV2-IgG or positive IGRA/cell-mediated immunity and history of typical symptoms
Exclusion criteria
Exclusion criteria: age <18 years old
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clicinical characteristics according to symptom questionnaires and QoL scores (SF-36, Chalder Fatigue Scale, PHQ) 3-24 months after acute COVID-19. Division in subcohorts according to dominant symptoms: 1. dyspnea (mMRC score) 2. fatigue (Chalder Fatigue Scale, SF-36) 3. cognitive impairment (MoCA) | — |
Secondary
| Measure | Time frame |
|---|---|
| - ability to work - rate of immunity (anti-SARS-CoV-2-IgG, Sars-CoV-2-IGRA [INF?-Release-Assay], cell-mediated immunity, autoantibodies, SARS-CoV-2-induced autoimmunity) - laboratory evaluation (inflammatory markers, endocrine profiling) - additional diagnostic evaluation (echocardiography, lung function tests, radiology) - physical and cognitive exercise testing (MoCA, grip strength testing) | — |
Countries
Germany
Contacts
Public ContactNelli Edel
Infektiologie, Klinik für Innere Medizin II/Universitätsklinikum Freiburg
Outcome results
None listed