Preoperative nTMS language mapping in brain tumor patients - a comparison of stimulation protocols

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00025317

Enrollment

Registered

2021-07-29

Start date

2019-05-12

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

R90.0

Interventions

Group 1: "historic" stimulation protocol Group 2: intensive peritumoral stimulation protocol Group 3: "20x20" stimulation protocol Group 4: sham stimulation

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: brain tumor in the dominant hemisphere; preoperative MRI

Exclusion criteria

Exclusion criteria: MRI contraindications; contraindications for transcranial magnetic stimulation (e.g. metal implants); pregnancy; severe aphasia

Design outcomes

Primary

Measure	Time frame
error rate and localization	—

Secondary

Measure	Time frame
error category; functional outcome	—

Countries

Germany

Contacts

Public ContactTizian Rosenstock

Klinik für Neurochirurgie, Charité-Universitätsamedizin Berlin

tizian.rosenstock@charite.de03045050

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026