Prospective evaluation of a new algorithm for the diagnosis of malnutrition sequentially employing NRS-2002 and phase angle assessed by bioelectric impedance analysis (BIA). A prospective cohort study with outcome evaluation.

Prospective evaluation of a new algorithm for the diagnosis of malnutrition sequentially employing NRS-2002 and phase angle assessed by bioelectric impedance analysis (BIA). A prospective cohort study with outcome evaluation. - SKD4

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00025307

Enrollment

4000

Registered

2021-05-27

Start date

2019-05-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Criteria for diagnosis of malnutrition, prevalence of hospital malnutrition

Interventions

Group 1: Epidemiologic study in a cohort of adult hospitalized patients allocated to group 1 high malnutrition risk or group 2 low malnutrition risk by means of nutrition risk screening (NRS-2002) bei

Eligibility

Sex/Gender

All

Age

18 Years to 110 Years

Inclusion criteria

Inclusion criteria: Admission to hospital

Exclusion criteria

Exclusion criteria: No informed consent, treatment in intensive care unit, treatment in obstectric unit

Design outcomes

Primary

Measure	Time frame
To establish sensitivity and specificity of NRS-2002 = 3 plus PA < 5th percentile as compared to SGA B or C as “gold-standard” to diagnose malnutrition.	—

Secondary

Measure	Time frame
To compare the performance of classification malnourished vs non-malnourished by NRS-2002 = 3 plus PA < 5th percentile vs new ESPEN criteria. To compare the performance of classification malnourished vs non-malnourished by SGA B or C vs new ESPEN criteria. To analyze the influence of cut-point values of standardized phase angle and NRS 2002 on the diagnostic performance in order to improve diagnostic accuracy. To validate the Pandora Score. To analyze LOS depending on NRS score and/or PA < 5th percentile in combination with Pandora Score and ICD classes based on competing risk methodology. To analyze hospital mortality depending on NRS score and/or PA < 5th percentile in combination with Pandora Score and ICD classes based on competing risk methodology. To analyze hospital readmission depending on NRS score and/or PA < 5th percentile in combination with Pandora Score and ICD classes based on competing risk methodology. To perform additional extensive explorative analyses in order to recover the structure behind the data. In particular, mapping subgroups to ICD-10 categories of malnutrition (E44.0, E44.1 and E43) will be proposed.	—

Measure

Time frame

To compare the performance of classification malnourished vs non-malnourished by NRS-2002 = 3 plus PA < 5th percentile vs new ESPEN criteria. To compare the performance of classification malnourished vs non-malnourished by SGA B or C vs new ESPEN criteria. To analyze the influence of cut-point values of standardized phase angle and NRS 2002 on the diagnostic performance in order to improve diagnostic accuracy. To validate the Pandora Score. To analyze LOS depending on NRS score and/or PA < 5th percentile in combination with Pandora Score and ICD classes based on competing risk methodology. To analyze hospital mortality depending on NRS score and/or PA < 5th percentile in combination with Pandora Score and ICD classes based on competing risk methodology. To analyze hospital readmission depending on NRS score and/or PA < 5th percentile in combination with Pandora Score and ICD classes based on competing risk methodology. To perform additional extensive explorative analyses in order to recover the structure behind the data. In particular, mapping subgroups to ICD-10 categories of malnutrition (E44.0, E44.1 and E43) will be proposed.

—

Countries

Germany

Contacts

Public ContactMathias Plauth

Klinik für Innere Medizin I, Städtisches Klinikum Dessau

mathias.plauth@klinikum-dessau.de+49 340 5011275

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 6, 2026