Pilot Study on the impact of timing of antimicrobial prophylaxis for elective Caesarean section at term on infant gut microbiome

Pilot Study on the impact of timing of antimicrobial prophylaxis for elective Caesarean section at term on infant gut microbiome - SectioBiom

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00025305

Enrollment

Registered

2021-05-26

Start date

2019-11-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

O82

Interventions

Group 1: Antibiotic after cord-clamping Group 2: antibiotic before skin incision

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: elective Caesarean section at term, no PROM, not in labor, no antibiotics for three months, no smoking, no diabetes, singleton pregnancy

Exclusion criteria

Exclusion criteria: preterm birth, labor, PROM, smoking, diabetes

Design outcomes

Primary

Measure	Time frame
microbiome signature of infants in the first days of life as determined by 16S rRNA gene sequencing and analysis of antibiotic resistance genes	—

Secondary

Measure	Time frame
microbiome composition at one month and one year of life and maternal risk for surgical site infections	—

Countries

Germany

Contacts

Public ContactVerena Bossung

Universitätsklinikum Schleswig-Holstein

verena.bossung@uni-luebeck.de+4945150041700

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026