Investigation to detect metabolic changes in the early phase of a critical illness

Investigation to detect metabolic changes in the early phase of a critical illness - MACI-E (Metabolic Alterations in Critical Illness - Early)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00025292

Enrollment

Registered

2023-03-01

Start date

2023-04-26

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

critical illnesses

Interventions

Group 1: Population: Severely ill patients with - Subarachnoid hemorrhage (Hunt&Hess 4 or 5) or - Intracranial bleeding or - Severe traumatic brain injury - all requiring mechnical ventilation Observ

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Severely ill patients with - Subarachnoid hemorrhage (Hunt&Hess 4 or 5) or - Intracranial bleeding or - Severe traumatic brain injury and - all requiring mechnical ventilation

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

Measure	Time frame
Profile of metabolic changes (e.g. blood lipids and amino acids) within the first three days of a critical illness	—

Countries

Germany

Contacts

Public ContactCaspar Stephani

Universitätsmedizin Göttingen

Caspar.Stephani@med.uni-goettingen.de+49-175-3431572

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026