The Predictive Value of D-Wave, Hand-Muscle MEPs and free-running EMG for the Upper Limbs’ Motor Outcome in Cervicothoracical Intramedullary Spinal Cord Tumor Microsurgery

The Predictive Value of D-Wave, Hand-Muscle MEPs and free-running EMG for the Upper Limbs’ Motor Outcome in Cervicothoracical Intramedullary Spinal Cord Tumor Microsurgery - D-Wave-IMSCT

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00025229

Enrollment

Registered

2021-05-03

Start date

2017-04-10

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

IMSCT Intramedullary spinal cord tumors

Interventions

Group 1: Prospective observation of outcome of all patients with resection of a cervical or thoracical IMSCT with the aid of multimodal IONM incl. D-Wave after consent for study participation.

Eligibility

Sex/Gender

All

Age

14 Years to 99 Years

Inclusion criteria

Inclusion criteria: All patients with resection of a cervical or thoracical IMSCT with the aid of multimodal IONM incl. D-Wave after consent for study participation

Exclusion criteria

Exclusion criteria: missing pre- and/or postop. status or resection without IONM

Design outcomes

Primary

Measure	Time frame
Evaluation of the predictive value of D-wave, hand-muscle TcMEPs and SSEPs for the distal limbs’ fine motor outcome after cervical imSCT surgery during resection of cervical and thoracical in comparison to lumbar intramedullary spinal cord tumors .	—

Secondary

Measure	Time frame
1.) Assessment of the pre- and postop. neurological status and identification of postop. new deficits with Special Focus on the upper extremities' fine-motor Outcome incl. finctional scores (Nine-hole Peg Test [NHPT], Modified Orthopaedic Association Score [mJOA], etc.) 2.) Assessment of Imaging and operative characteristics of the study population 3.) Evaluation of feasibility of standard-IONM and analysis of intraoperative IONM-findings (with special focus on D-Wave) 4.) Correlation between IONM-findings (with special focus on D-Wave) and surgical-anestehsiological findings and procedural steps 5.) Correlation between IONM-findings (with special focus on D-Wave) abd postoperative neurological outcome (with special focus on upper extremities' fine-motor outcome) to clarify the predictive potential of IONM, esp. D-Wave 6.) Evaluation of IONM-warning criteria with regard to predictive potential and statistical Evaluation to establish new warning criteria 7.) Additional assessment of Quality-of-life and fine-motor-Outcome of the upper extremities fincl. functional scores (Nine-hole Peg Test [NHPT], Modified Orthopaedic Association Score [mJOA], etc.) via telephone interviews/questionaires and clinical examination for Long-term Outcome Analysis in case of patient's consent	—

Measure

Time frame

1.) Assessment of the pre- and postop. neurological status and identification of postop. new deficits with Special Focus on the upper extremities' fine-motor Outcome incl. finctional scores (Nine-hole Peg Test [NHPT], Modified Orthopaedic Association Score [mJOA], etc.) 2.) Assessment of Imaging and operative characteristics of the study population 3.) Evaluation of feasibility of standard-IONM and analysis of intraoperative IONM-findings (with special focus on D-Wave) 4.) Correlation between IONM-findings (with special focus on D-Wave) and surgical-anestehsiological findings and procedural steps 5.) Correlation between IONM-findings (with special focus on D-Wave) abd postoperative neurological outcome (with special focus on upper extremities' fine-motor outcome) to clarify the predictive potential of IONM, esp. D-Wave 6.) Evaluation of IONM-warning criteria with regard to predictive potential and statistical Evaluation to establish new warning criteria 7.) Additional assessment of Quality-of-life and fine-motor-Outcome of the upper extremities fincl. functional scores (Nine-hole Peg Test [NHPT], Modified Orthopaedic Association Score [mJOA], etc.) via telephone interviews/questionaires and clinical examination for Long-term Outcome Analysis in case of patient's consent

—

Countries

Germany

Contacts

Public ContactAndrea Szelenyi

LMU München

andrea.szelenyi@med.uni-muenchen.de0049440073540

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026