Study for the evaluation of a mobile application for independent cognitive training - effects on cognitive abilities and quality of life of patients with mild cognitive disorders

Study for the evaluation of a mobile application for independent cognitive training - effects on cognitive abilities and quality of life of patients with mild cognitive disorders - NeuroNation MED - Effect study (NeNaE)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00025133

Enrollment

286

Registered

2021-11-05

Start date

2021-07-11

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F06.7 U09.9

Interventions

Group 1: Intervention group (patients with mild cognitive disorder): app-based cognitive training over a period of 12 weeks with 3 training sessions per week Group 2: Wait list control group (patients

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Arm 1 & 2 : - Age = 18 years - Existing diagnosis of mild cognitive impairment (ICD-10: F06.7) - Mild cognitive impairment (TICS (Telephone Interview for Cognitive Status) >20 and < 33). - Ability to consent - Ability and experience in using a mobile device to use the app - Able to understand instructions in German language - Presence of a mobile device to use the app. Arm 3 & 4 : Post-Covid. - Age = 18 years - Current diagnosis of mild cognitive disorder (ICD-10: F06.7) and post-Covid condition (ICD-10 U09.9) Diagnosis - Capacity to consent - Ability and experience in using a mobile device to use the app

Exclusion criteria

Exclusion criteria: Exclusion criteria (all arms): - Severe cognitive impairment (TICS <21). - Presence of moderate or severe dementia - Legal care - Paresis of the dominant arm or hand - Visual field defects (e.g., hemianopsia, quadranta-nopsia) - Severe non-correctable visual impairment (unable to visually recognize app content) - Severe aphasia that impairs instructional comprehension - Use of other apps and software (training products) that provide cognitive training

Design outcomes

Primary

Measure	Time frame
Cognitive abilities, measured with the Neuropsychological Assessment Battery (NAB) at two visits	—

Secondary

Measure	Time frame
Understanding of health and health information (Health Literacy Questionnaire, HLQ), subjective cognitive ability (Cognitive Failure questionnaire, CFQ), psychosocial health (Health-49, Dimension B - Psychological Well-Being and Dimension D - Self-Efficacy), depressive symptoms (Hospital Anxiety and Depression Scale, HADS), Usability (System Usability Scale, SUS), patient diary of the additional cognitive activating training performed and the respective training duration	—

Measure

Time frame

Understanding of health and health information (Health Literacy Questionnaire, HLQ), subjective cognitive ability (Cognitive Failure questionnaire, CFQ), psychosocial health (Health-49, Dimension B - Psychological Well-Being and Dimension D - Self-Efficacy), depressive symptoms (Hospital Anxiety and Depression Scale, HADS), Usability (System Usability Scale, SUS), patient diary of the additional cognitive activating training performed and the respective training duration

—

Countries

Germany, Luxembourg

Contacts

Public ContactRebecca Dahms

Forschungsgruppe Geriatrie Charité - Universitätsmedizin Berlin

rebecca.dahms@charite.de+49 30 450 553 696

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 9, 2026