K05.1
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: a) generalized gingivitis (BOP>30% (Chapple et al., 2018)); b) a minimum of 20 teeth; c) aged 18 to 49 with a BMI of 18-30 kG/m2; d) self-reported Western diet conditions with daily intake of processed carbohydrates, sugar, animal protein and other WD-characteristics assessed by verbal anamnesis
Exclusion criteria
Exclusion criteria: a) presence of periodontitis (CPITN (Ainamo et al. 1982) two times >2); b) smoking; c) severe illnesses (e.g. HIV, chronic hepatitis, cancer, illnesses of the salivary glands or the gastrointestinal tract, diabetes mellitus); d) pregnancy or breast feeding; e) intake of antibiotics within 6 months prior or during study; f) intake of anti-inflammatory drugs; g) on medication affecting gingival bleeding; h) intake of probiotics; i) strict vegetarian or vegan, low carb or paleo diet; j) dislike or intolerance of fish, milk, milk products; k) allergic to fish, fruits, nuts; l) eating disorder (anorexia nervosa, bulimia, binge eating, or fasting).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in the clinical parameter "bleeding on probing (%)" between the time before the test group started the diet and after six weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in other oral examination parameters: Gingival index (inflammation), plaque quantity. Additionally: supragingival microbiome, intestinal microbiome, serum fatty acids (omega-FS profile). | — |
Countries
Germany
Contacts
Poliklinik für Zahnerhaltung, Universitätsklinikum Heidelberg