Skip to content

Effect of the Mediterranean Diet on gingivitis. A randomized controlled trial

Effect of the Mediterranean Diet on gingivitis. A randomized controlled trial - GiMed

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00025103
Enrollment
34
Registered
2021-07-26
Start date
2020-01-21
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K05.1

Interventions

Group 1: Conversion from the habitual "Western" diet to the principles of a Mediterranean diet according to the most recently updated Mediterranean food pyramid from 2010. Nutrition training within th

Sponsors

Poliklinik für Zahnerhaltung, Universitätsklinikum Tübingen
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 49 Years

Inclusion criteria

Inclusion criteria: a) generalized gingivitis (BOP>30% (Chapple et al., 2018)); b) a minimum of 20 teeth; c) aged 18 to 49 with a BMI of 18-30 kG/m2; d) self-reported Western diet conditions with daily intake of processed carbohydrates, sugar, animal protein and other WD-characteristics assessed by verbal anamnesis

Exclusion criteria

Exclusion criteria: a) presence of periodontitis (CPITN (Ainamo et al. 1982) two times >2); b) smoking; c) severe illnesses (e.g. HIV, chronic hepatitis, cancer, illnesses of the salivary glands or the gastrointestinal tract, diabetes mellitus); d) pregnancy or breast feeding; e) intake of antibiotics within 6 months prior or during study; f) intake of anti-inflammatory drugs; g) on medication affecting gingival bleeding; h) intake of probiotics; i) strict vegetarian or vegan, low carb or paleo diet; j) dislike or intolerance of fish, milk, milk products; k) allergic to fish, fruits, nuts; l) eating disorder (anorexia nervosa, bulimia, binge eating, or fasting).

Design outcomes

Primary

MeasureTime frame
Change in the clinical parameter "bleeding on probing (%)" between the time before the test group started the diet and after six weeks.

Secondary

MeasureTime frame
Change in other oral examination parameters: Gingival index (inflammation), plaque quantity. Additionally: supragingival microbiome, intestinal microbiome, serum fatty acids (omega-FS profile).

Countries

Germany

Contacts

Public ContactValentin Bartha

Poliklinik für Zahnerhaltung, Universitätsklinikum Heidelberg

valentin.bartha@med.uni-heidelberg.de062215639888

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026