Effectiveness of preoxygenation by conventional face mask versus non-invasive ventilation in morbidly obese patients: measurable by the oxygen-reserve index?

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00025023

Enrollment

Registered

2021-04-16

Start date

2017-05-10

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

E66.02

Interventions

Group 1: Morbidly obese patients of legal age

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: BMI >=35

Exclusion criteria

Exclusion criteria: structural lung disease

Design outcomes

Primary

Measure	Time frame
This study investigates, if effectiveness of preoxygenation in morbidly obese patients performed either via facemask, or by NIV can be assessed by ORI. Parameters were: SpO2, ORI, HR, BP, arterial BGA and (if applicable) ventilation parameters Measuringpoints: 0: baseline 1: after 5 min of 100% oxygen 2: after 20 min of room air (restoring baseline) 3: after 5 min of NIV with 100% oxygen 4: after intubation 5: ventilation with 100% oxygen 6: seconds until decreasing ORI, decreasing SpO2, ORI=0 and SpO2=92% 7: ventilation with standardized parameters	—

Measure

Time frame

This study investigates, if effectiveness of preoxygenation in morbidly obese patients performed either via facemask, or by NIV can be assessed by ORI. Parameters were: SpO2, ORI, HR, BP, arterial BGA and (if applicable) ventilation parameters Measuringpoints: 0: baseline 1: after 5 min of 100% oxygen 2: after 20 min of room air (restoring baseline) 3: after 5 min of NIV with 100% oxygen 4: after intubation 5: ventilation with 100% oxygen 6: seconds until decreasing ORI, decreasing SpO2, ORI=0 and SpO2=92% 7: ventilation with standardized parameters

—

Secondary

Measure	Time frame
Secondly, this study examines, if differences in the effectiveness of preoxygenation via face mask or NIV can be monitored by ORI.	—

Countries

Germany

Contacts

Public ContactJanina Kosan

Klinik für Anästhesiologie Universitätsklinikum Hamburg-Eppendorf

j.kosan@uke.de+4915222527362

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 13, 2026