U09.9 I41.1
Conditions
Interventions
Group 1: adults, whose COVID-19 is at least 4 months ago, undergo cardiovascular magnetic resonance imaging and 3D electrocardiography
Group 2: data on cardiovascular magnetic resonance and 3d electro
Sponsors
Universitätsklinikum Heidelberg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Age of at least 18 years and ability to consent - COVID-19 at least 4 months ago - proven by SARS-Cov-2 PCR or antibody test
Exclusion criteria
Exclusion criteria: - Contraindications to MRI examinations - especially MRI incompatible implants, clinical instability and severe claustrophobia. - Heart failure that existed prior to COVID-19 - Myocardial diseases (heart failure, cardiomyopathies, myocarditis) that existed prior to COVID-19 - Coronary artery disease, which requires or required coronary intervention and myocardial infarction. - Prior cardiac surgery (e.g., bypass) and device implantation (e.g., heart valves, PFO occluders) - Atrial fibrillation that existed prior to COVID-19 - Active cancer - Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Changes in cardiac morphology (e.g. ventricular and atrial dimensions, myocardial mass) - Changes in left and right ventricular ejection fraction - Impairment of the global longitudinal strain, the long axis strains as well as segmental strains - Proportion of myocardial segments with pathological strain values - Changes in myocardial T1 and T2 - Changes in the 3D electrocardiogram | — |
Secondary
| Measure | Time frame |
|---|---|
| - Changes in the subjective physical performance - Occurence or persistence of COVID-19 associated symptoms - Assessment of computer-based techniques for image analysis and diagnostics | — |
Countries
Germany
Contacts
Public ContactFlorian André
Universitätsklinikum Heidelberg - Klinik für Kardiologie, Angiologie und Pneumologie
Outcome results
None listed