The use of Virtual Reality in psychotherapy for depression

The use of Virtual Reality in psychotherapy for depression - DeepVR

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

DRKS

Registry ID

DRKS00024981

Enrollment

Registered

2021-04-07

Start date

2021-06-07

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F32 F33 F34

Interventions

Group 1: DeepVR VR-Intervention The Deep-VR intervention consists of two VR modules. 1. VR mindfulness module: at the beginning of the inpatient stay, interested patients are provided with the VR mind

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: - Depression symptomatology (ICD-10: F32 - 34) - Inpatient treatment at the clinic for Psychosomatics and Psychotherapy, LVR-Klinikum Düsseldorf

Exclusion criteria

Exclusion criteria: - COVID-19 disease in an infectious phase or symptoms suggestive of COVID-19 disease. - Last alcohol consumption less than 8 hours ago - insufficient knowledge of the German language - uncorrected visual loss and visual disturbances - insufficiently corrected hearing - Neurological/psychiatric pre-existing diseases affecting the vestibular organ, impairing the sense of balance or altering visual perception (e.g. Meniere's disease, dementia, post-stroke condition, psychosis) - known epilepsy - taking medications that affect eye movements (lithium, carbamazepine, lamotrigine, topiramate, phenytoin, risperidone, haloperidol, phenobarbital or primidone) - a body mass index (BMI) less than or equal to 17

Design outcomes

Primary

Measure	Time frame
BDI-II (Beck-Depression Inventar), Paper-Pencil questionaire, Depression severity, pre measurement (study inclusion) & post-measurement (end of inpatient treatment in clinic). Four statements are given for each of 21 symptoms of depression (based on the DSM-IV criteria for major depression), from which the one that best describes how the assessor has felt in the past two weeks is to be selected. Completion time: between 5 and 10 minutes. Numerous studies have used the BDI-II (Cronbach's Alpha Depressed Patients in Treatment (N = 288) = .93). In different samples, there were high levels of agreement with both self-rated depressiveness (FDD-DSM-IV), r = .72 to .89, and with other-rated depressiveness (MADRS), r = .68 to .70.	—

Measure

Time frame

BDI-II (Beck-Depression Inventar), Paper-Pencil questionaire, Depression severity, pre measurement (study inclusion) & post-measurement (end of inpatient treatment in clinic). Four statements are given for each of 21 symptoms of depression (based on the DSM-IV criteria for major depression), from which the one that best describes how the assessor has felt in the past two weeks is to be selected. Completion time: between 5 and 10 minutes. Numerous studies have used the BDI-II (Cronbach's Alpha Depressed Patients in Treatment (N = 288) = .93). In different samples, there were high levels of agreement with both self-rated depressiveness (FDD-DSM-IV), r = .72 to .89, and with other-rated depressiveness (MADRS), r = .68 to .70.

—

Secondary

Measure	Time frame
PSSUQ (Post Study System Usability Questionaire), global Usability of the VR-Intervention, post-measurement (end of inpatient treatment in clinic)	—

Countries

Germany

Contacts

Public ContactSteffen Holsteg

Universitätsklinikum Düsseldorf, Klinisches Institut für Psychosomatische Medizin und Psychotherapie

steffen.holsteg@med.uni-duesseldorf.de02118116211

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026