G35
Conditions
Interventions
Group 1: To investigate the role of calcium on the activation and differentiation of peripheral blood mononuclear cells (T cells, B cells and monocytes) in patients with hypertension, which received a
Sponsors
Universitätsmedizin Göttingen
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: • In the group of patients without CCB therapy, no CCB therapy for at least 3 months • In the cohort of patients with CCB therapy, no CCB therapy for at least 3 months • Patients who have given written informed consent based on GCP guidelines
Exclusion criteria
Exclusion criteria: • Pregnancy • Known autoimmune disease • Acute/chronic infection • Active Malignancy • Chronic kidney disease > CKD stage 4 • Hypo-/Hypercalcemia • Intake of calcium, vitamin D and its derivates • Calcineurin-inhibitor treatment • Therapy with calcimimetica • Hyperparathyreoidism • Patients who have not given written informed consent based on GCP guidelines
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To investigate the role of calcium on the activation and differentiation of peripheral blood mononuclear cells (T cells, B cells and monocytes) in patients with hypertension, which received a calcium antagonist therapy, as compared to hypertensive patients without a calcium antagonist treatment. | — |
Countries
Germany
Contacts
Public ContactMartin Weber
Universitätsmedizin Göttingen
Outcome results
None listed