Skip to content

Clinical Trial for Preoperative High Intensity Interval Training (HIT) Prior to Oncological Esophagectomy

Clinical Trial for Preoperative High Intensity Interval Training (HIT) Prior to Oncological Esophagectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00024938
Enrollment
20
Registered
2021-09-20
Start date
2021-06-01
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C15.1

Interventions

Group 1: Intervention Group receiving four weeks of high intensity interval training with 16 intervals of 30 seconds of 95% VO2max and 30 seconds of 70% VO2max

Sponsors

Universitätsklinikum Mannheim
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: - Age between 18 and 80 years - male and female participants with histological diagnosis of andeocarcinoma or squamous cell carcinoma of the esophagus - non-palliative surgical therapy of esophageal cancer at University Hospital Mannheim - Written consent of the participant - four-week time span free of radiotherapy or chemotherapy ahead of surgical therapy - physical ability for ergometric testing on a bicycle

Exclusion criteria

Exclusion criteria: - Patients with severe cardiac or pulmonary disease - physical inability for ergometry test on a bicycle - missing ability for consent - language barrier - predictable non-compliance - non-resectable esophageal cancer - pregnancy - time-span short of four weeks prior to surgical therapy and after ending of radiotherapy or chemotherapy

Design outcomes

Primary

MeasureTime frame
feasibility of a four-week training program prior to surgical therapy

Secondary

MeasureTime frame
As a secondary endpoint we will investigate, if there is a change in musclemass, nutritional status via lab results, postoperative pain, postoperative complications as well as mean hospital stay when comparing patients receiving preoperative physical training and patients not receiving physical training. Furthermore, we would like to document laboratory parameters, perceived physical fitness, measured physical fitness, BMI and inflammatory markers prior to training, prior to surgery and after surgery.

Countries

Germany

Contacts

Public ContactAlida Finze

Universitätsklinikum Mannheim

alida.finze@umm.de06213832225

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: May 1, 2026