C15.1
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - Age between 18 and 80 years - male and female participants with histological diagnosis of andeocarcinoma or squamous cell carcinoma of the esophagus - non-palliative surgical therapy of esophageal cancer at University Hospital Mannheim - Written consent of the participant - four-week time span free of radiotherapy or chemotherapy ahead of surgical therapy - physical ability for ergometric testing on a bicycle
Exclusion criteria
Exclusion criteria: - Patients with severe cardiac or pulmonary disease - physical inability for ergometry test on a bicycle - missing ability for consent - language barrier - predictable non-compliance - non-resectable esophageal cancer - pregnancy - time-span short of four weeks prior to surgical therapy and after ending of radiotherapy or chemotherapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| feasibility of a four-week training program prior to surgical therapy | — |
Secondary
| Measure | Time frame |
|---|---|
| As a secondary endpoint we will investigate, if there is a change in musclemass, nutritional status via lab results, postoperative pain, postoperative complications as well as mean hospital stay when comparing patients receiving preoperative physical training and patients not receiving physical training. Furthermore, we would like to document laboratory parameters, perceived physical fitness, measured physical fitness, BMI and inflammatory markers prior to training, prior to surgery and after surgery. | — |
Countries
Germany
Contacts
Universitätsklinikum Mannheim