An observational clinical study to assess and assessment of the risk of bleeding after dentoalveolar procedures with Medication with direct oral anticoagulants (DOAKs), antiplatelet agents, and vitamin K antagonists.

An observational clinical study to assess and assessment of the risk of bleeding after dentoalveolar procedures with Medication with direct oral anticoagulants (DOAKs), antiplatelet agents, and vitamin K antagonists. - DOAC

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00024889

Enrollment

300

Registered

2021-03-29

Start date

2019-04-03

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A01 Z92.1 A01

Interventions

Group 1: Extraction of tooth

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patient is taking DOACs (dabigatran, rivaroxaban, apixaban, or edoxaban), antiplatelet agent, vitamin K antagonist - Oral surgery procedures include implant placement, tooth extraction, Flapoplasties, osteotomies (more specifically, up to 3 implants and 3 teeth per jaw, osteotomies of teeth (including wisdom teeth), augmentations limited to sinus lift in the upper jaw with one or two implants)

Exclusion criteria

Exclusion criteria: the oral surgery is performed under intubation anesthesia and/or inpatient admission is inpatient admission is necessary preoperatively - Patient with congenital hemorrhagic diathesis - Larger augmentations (bone block chin or jaw angle) or if a second second surgical area is necessary for this - Patients with co-morbidities that preclude local and ambulatory treatment exclude local and outpatient treatment, the risk of bleeding is assessed as increased

Design outcomes

Primary

Measure	Time frame
Postoperative Bleeding risk as a function of anticoagulation and surgical Intervention within the first 10 days postoperatively	—

Secondary

Measure	Time frame
Derivation of risk stratification for anticoagulated patients and postoperative rebleeding.	—

Countries

Germany

Contacts

Public ContactMayte Buchbender

Mund-Kiefer- und GesichtschiurgieZMK Klinik, FAU Erlangen

mayte.buchbender@uk-erlangen.de09131-8533614

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 21, 2026